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Pathology and Laboratory Medicine, Faculty of Medicine

PATH: Pathology

PATH 300 (6) Background to Medical Laboratory Science
Introductory lectures and laboratory sessions in clinical chemistry, haematology and blood banking, hospital microbiology, preparation and examination of tissue sections. For Medical Laboratory Science students without previous experience in hospital laboratories. [3-4; 0-0]
Prerequisite: All of BIOL 112, BIOL 200, BIOL 201, CHEM 123, CHEM 205, CHEM 233, CHEM 235, MICB 202.
PATH 301 (4) Basic and Physical Biochemistry for Medical Laboratory Scientists
An integrated approach to specific areas of the theoretical and practical aspects of those physical and biological sciences relevant to medical laboratory science. Emphasis will be placed upon the application of basic science to those clinical disciplines practised by the medical laboratory scientist, e.g., histochemistry, clinical chemistry, microbiology, haematology, etc.
PATH 303 (4) Cytogenetics, Molecular Genetics, Tissue Culture & Cytology
Fundamentals of human genetics and molecular biology as they relate to studying and detecting disease in a population; tissue culture techniques to assess cell viabilities; cytomorphology principles in disease detection.
PATH 304 (4) Normal Human Histology
An advanced lecture and laboratory course in the microscopic structure of the human body necessary for a complete understanding of histochemistry and histopathology.
PATH 305 (3) Modern Microscopy
Theoretical and practical application of widely used microscopy techniques.
PATH 306 (2) Laboratory Safety for Medical Laboratory Scientists
Control processes for workplace hazards of radiological, chemical, and biological origin.
PATH 327 (4) Bacteriology, Mycology, Virology and Parasitology
Descriptions of each group of human microbial pathogens according to biological attributes, clinical features, pathogenesis and pathology, epidemiology, immunological reactions, laboratory diagnosis, principles of antimicrobial therapy, preventative measures. For students in the Faculty of Medicine B.M.L.Sc.
PATH 375 (3) Introduction to Human Pathology
A lecture-demonstration course designed to acquaint students in the allied health professions with a basic understanding of the causes, natural history, and pathophysiology of common disease processes.
Prerequisite: 6 credits each first year BIOL and CHEM
PATH 402 (4) Medical Laboratory Science: Haematology
A theoretical and practical examination of those modern concepts of haematology which relate to the practice of medical laboratory science.
PATH 404 (6) Diagnostic Histochemistry
A lecture and laboratory course that encompasses the theory and the practice of currently available histochemical techniques. This course is to supplement the histopathological technique course taken as a requirement for CSLT (RT).
Prerequisite: Certification.
PATH 405 (3) Seminars in Current Topics
Oral and written presentation and critical appraisal of scientific papers.
PATH 406 (6) Clinical Chemistry
This course will review and discuss the methodology of clinical chemistry in order to put these analytical methods into the broad perspective of the pathophysiology of human disease and biochemistry.
PATH 407 (3) Medical Laboratory Toxicology: Analytical, Clinical
A theoretical and practical examination of analytical and pathophysiological aspects of clinical and forensic toxicology.
PATH 408 (3) Research and Career Skills
Overall operation of research laboratories including roles of personnel and funding; communication of scientific research; career skills and pathways; communication, collaboration, presentations and peer-assessment skills.
PATH 415 (2) Immunopathology
Immunological events causing tissue injury.
PATH 417 (3/6) c Human Bacterial Infections
Students acquire content relating to the virulence factors of the bacteria and the pathophysiology of the host while working through case scenarios on their own and in online groups. Students taking this course must be willing to engage in both self-directed and small-group learning.
Prerequisite: MICB 202. Or equivalent.
PATH 427 (3) Basic Principles of Infection Prevention and Control
This course provides the basic principles to prevent the spread of microorganisms pathogenic to humans. It may be taken towards a Certificate in Infection Control.
PATH 437 (3) Viral Infections in Humans
Interactions between viruses and humans; pathogenesis; prompt virological diagnosis; rationale for antiviral chemotherapy and prophylaxis. [3-0-0]
Equivalency: MICB 407.
PATH 438 (2-6) c Medical Laboratory Science: Directed Studies
Investigation of a specific topic in Medical Laboratory Science. Permission of the department head is required.
PATH 447 (3) Directed Studies
An elective in clinical infection control, medical microbiology or molecular biology.
Prerequisite: All of PATH 427, PATH 467.
PATH 448 (2) Introduction to Laboratory Medicine
An elective course open to first-year medical students who spend at least three consecutive hours each week in one of the affiliated hospitals of the Department of Pathology, Vancouver Hospital, under the joint supervision of a Senior Resident in Pathology and the Professional Staff of the following Divisions: anatomical pathology, clinical biochemistry, haematology, pediatric pathology. Enrolment is limited.
PATH 450 (0) Systemic Pathology
A series of Pathology discussions in conjunction with various clinical departments designed to illustrate the role of Pathology in the diagnosis and management of various diseases.
PATH 451 (3) Clerkship in Laboratory Medicine and Infection Prevention and Control
May involve attendance at an approved institution and/or a project assigned by the instructor(s). Instructor permission required. Enrolment may be limited.
PATH 452 (3) Clerkship in Anatomic Pathology
An elective course open to third-year medical students, designed to familiarize the student with Anatomic Pathology, including Surgical Pathology, Pediatric Pathology, Autopsy Pathology and Cytology. This elective may involve attendance at one or more affiliated hospitals. Registration requires consent of the Department and enrolment may be limited.
PATH 453 (0) Clinical Laboratory Haematology
Correlative seminars based on haematology case studies relating clinical features to laboratory investigations.
Equivalency: MEDI 452.
PATH 457 (3) Clinical Laboratory Microbiology
Selected clinical laboratory exercises plus seminars to illustrate the diagnosis and management of patients with microbial infections. Elective course limited to third- and fourth-year medical students.
Prerequisite: Departmental approval required.
PATH 467 (3) Basic Microbiology for Infection Control
The identification, clinical significance, and transmission of pathogenic organisms are presented. This course is available by correspondence or webCT. It may be taken towards fulfillment of the Certificate in Infection Control.
PATH 477 (3) Basic Epidemiology for Infection Control
Epidemiology, study, design and analysis, and outbreak investigation as it applies to institutional infection control.
Equivalency: SPPH 401.
PATH 501 (2) Foundations of Human Histopathology
Microscopic anatomy of human tissues and organs in health and disease. Principles of histological analysis and applications in pathology. This course is not eligible for Credit/D/Fail grading.
PATH 502 (2) Current Topics in Pathology Research
General principles of etiology, pathogenesis, disordered physiology, and anatomic pathology of common disease processes. This course is not eligible for Credit/D/Fail grading.
PATH 518 (2-4) c Pulmonary Pathophysiology
A review of current topics in pulmonary pathophysiology at an advanced level suitable for graduate students majoring in pathology, medicine, surgery or anaesthesiology. Topics will include lung anatomy, ventilation, blood flow, gas and fluid exchange. This course is not eligible for Credit/D/Fail grading.
Prerequisite: One of PHYL 301, PHYL 303, PHYL 400.
PATH 521 (3) Introduction to the Pathogenesis of Human Disease
Current medical research; cardiovascular and pulmonary disease. This course is not eligible for Credit/D/Fail grading.
Prerequisite: Permission of instructor.
PATH 523 (3) Principles of Antimicrobial Chemotherapy
Classification, structure and mode of action of antimicrobial agents. In-depth comparison of factors affecting the activity of antimicrobials in vivo and in vitro. This course is not eligible for Credit/D/Fail grading.
Prerequisite: All of MICB 200, PATH 427.
PATH 527 (2-4) d Bacteriology, Mycology, Virology and Parasitology
All groups of microorganisms pathogenic for humans. Clinical features, pathogenesis and pathology, epidemiology, properties of the agents, immunology, laboratory diagnosis, therapy, preventative measures. This course is not eligible for Credit/D/Fail grading.
PATH 530 (3) Nutrition and Metabolic Aspects of Human Disease
Molecular effects of changes in nutrient status and metabolism on health. This course is not eligible for Credit/D/Fail grading.
Prerequisite: Restricted to students registered in the Pathology Graduate Program or instructor approval required.
PATH 531 (3) Molecular and Cell Biology of Cancer
This course focuses on molecular and cell biology of cancer and consists of a series of lectures/reviews combined with discussions and presentations by students on the topics selected by the instructors. Emphasis will be on students' presentations and discussion. This course is not eligible for Credit/D/Fail grading. [3-0]
Prerequisite: MEDG 421 is recommended. Course coordinator approval is required.
Equivalency: MEDG 521.
PATH 535 (2) Seminar
Attendance required of all M.Sc. candidates in the Department. This course is not eligible for Credit/D/Fail grading.
PATH 547 (3) Techniques in Molecular Biology and Experimental Pathology
Nucleic acid purification and characterization; restriction enzyme digests; northern and southern blotting; cloning; DNA sequencing; polymerase chain reaction technology; electron microscopy; fluorescein-activated cell sorting. This course is not eligible for Credit/D/Fail grading. [0-6]
PATH 548 (1-12) c Directed Studies
This course is not eligible for Credit/D/Fail grading.
PATH 549 (18) M.Sc. Thesis
Honours/Pass/Fail. This course is not eligible for Credit/D/Fail grading.
PATH 570 (3) Cardiovascular Pathophysiology
Pathogenesis, abnormal physiology, and therapeutic approaches in heart disease including cardiac arrhythmia, heart failure, myocardial infarction, hypertension, atherosclerosis. This course is not eligible for Credit/D/Fail grading.
PATH 582 (3) Toxicology III: Environmental Toxicology
Toxicology and risk assessment of air, water and soil pollutants; food additives; animal and plant toxins; pesticides; heavy metals; solvents. This course is not eligible for Credit/D/Fail grading. [3-0-0]
Equivalency: PHAR 582.
PATH 583 (3/4) d Toxicology IV: Molecular Mechanisms of Toxicology
Activation versus detoxification by cytochromes P-450; the role of the Ah receptor; reactive oxygen species; heavy metals; apoptosis. This course is not eligible for Credit/D/Fail grading. [3-0-0]
Equivalency: PHAR 583.
PATH 635 (2) Seminar
Attendance required for all Ph.D. candidates in the department. This course is not eligible for Credit/D/Fail grading.
PATH 649 (0) Doctoral Dissertation
PATH 700 (0) Pathology Conference
Review and analysis of current cases. Diagnostic and pathogenic significance of findings are assessed. One hour weekly.
PATH 701 (0) Surgical Pathology
Five days per week, one hour review of current diagnostic biopsy problems. Diagnostic and therapeutic implications are discussed.
PATH 702 (0) Haematologic Pathology
Lectures and seminars on the pathology of haematological diseases. Two hours weekly.
PATH 703 (0) Histochemical Pathology
A series of lectures and seminars to show current applications of histochemical techniques to contemporary pathological diagnosis. One hour weekly per quarter.
PATH 704 (0) Haematologic Pathology
Analysis of pathology of bone marrow aspirates; taken in one half or whole year. One and one half hours weekly.
PATH 705 (0) Clinical Chemistry
A series of lectures, seminars, tutorials, and laboratory tuition to demonstrate the use of chemical analysis in clinical medicine. Two hours weekly.
PATH 706 (0) Neuropathology
Sectioning of necropsy material with clinicopathological correlation. One hour weekly.
PATH 707 (0) Neuropathology, Clinical Correlation
Pathology of central nervous system disease demonstrated to clinical staff, stressing correlation with clinical diseases. Two hours weekly.
PATH 708 (0) Dermatopathology
Clinicopathological correlation of dermal lesions. Discussion of pathogenesis, clinical course, and prognostic implications. One hour weekly.
PATH 709 (0) Renal Biopsy Rounds
Weekly correlation between clinical status and pathological findings in several patients.
Equivalency: MEDI 711.
PATH 710 (0) Hepatic and Gastrointestinal Pathology
Clinicopathologial correlation of hepatic and gastrointestinal biopsy material with discussions of pathogenesis, etiology, and therapeutic implications. Alternate weeks, one hour.
PATH 711 (0) Cytology
Daily review of cytopathology. Analysis of cervical and sputum smears and pleural, gastric, and bronchial aspirates with discussion of significance to patients, taken in one quater of year.
PATH 712 (0) Perinatal Mortality Conference
Discussion of perinatal mortality cases for the month, with review of clinical and laboratory findings, management, and pathology findings by pediatric, obstetrical, and pathology teaching staff. Methods of possible prevention of foetal or neonatal death are discussed and recommended as hypothetical reasons for preventability, where appropriate. Two hours monthly.
PATH 713 (0) Seminars in Biochemical Pediatrics
A series of discussions on clinical problems which are chosen to illustrate the biochemical basis for the practice of pediatrics.
PATH 714 (0) Pediatric Pathology
Demonstration and dissection of congenital heart lesions; correlation of cardiological and pathological data. One hour weekly.
PATH 720 (0) Microbiological Diagnosis
Conduct of bacterial, fungal, parasitological, and viral laboratory tests relevant to the microbiological examination of patients. For medical residents.
PATH 721 (0) Microbiological Research
Conduct of research on some aspect of clinical or basic microbiology. For medical residents.
PATH 722 (0) Microbial Infections
Review in depth of syndromes caused by common human pathogenic bacteria, fungi and viruses, including principles of current laboratory diagnostic procedures and the rational use of antibiotics and prophylactic agents. For medical residents.
PATH 725 (0) Histopathology of Infectious Diseases
Gross and microscopic changes associated with infections, and the pathophysiology involved in their development. The course includes seminars based on histological specimens. For residents in Medical Microbiology, General and Anatomical Pathology, and Infectious Diseases.
PATH 730 (0) Clinical Nuclear Medicine
See RADI 710.
PATH 731 (0) Progress in Nuclear Medicine
See RADI 711.
PATH 732 (0) Clinical Investigation/Research
See RADI 712.
PATH 733 (0) Quality Correlation in Nuclear Medicine
See RADI 713.

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