Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences

PHAR 180 (1) Pharmaceutical Topics and Communication Seminar I

Current topics in the Pharmaceutical Sciences and basic skills for a short presentation on a biological science topic. This course is not eligible for Credit/D/Fail grading.

PHAR 202 (3) Biochemical Pharmacology

Biochemical pharmacology including fundamental aspects of enzymology, biochemistry, enzyme kinetics, drug metabolism and pharmacokinetics. This course is not eligible for Credit/D/Fail grading.

PHAR 203 (4) Drug Delivery Technologies and Personalized Medicine Theory and Laboratory

Theoretical and practical knowledge of biopharmaceuticals, pharmaceutics, formulations, nanomedicine, and precision medicine as they apply to pharmaceutical sciences. This course is not eligible for Credit/D/Fail grading.

PHAR 204 (3) Pharmaceutical Research

Types of research scientists in academia and industry across the broad range of pharmaceutical science disciplines. This course is not eligible for Credit/D/Fail grading.

PHAR 205 (3) Clinical Epidemiology & Pharmaceutical Outcomes I

Population-level study designs and critical appraisal skills in evidence evaluation, with a special emphasis on evidence-based pharmacy practice. This course is not eligible for Credit/D/Fail grading.

Prerequisite: One of STAT 200, BIOL 300.

PHAR 280 (3) Pharmaceutical Topics and Communication Seminar II

Current topics in the pharmaceutical and biotechnology industries and intermediate level skills for a short presentation. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 180.

PHAR 302 (3) Pharmacokinetics and Pharmacogenomics

Basic pharmacokinetic concepts: metabolism, clearance, volume of distribution, half-life, and hepatic clearance. Basic pharmacogenomics concepts of genetic polymorphism. This course is not eligible for Credit/D/Fail grading.

PHAR 303 (3) Nanomedicine

Advanced nanomedicine concepts for drug packaging, delivery, and efficacy. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 202.

PHAR 304 (4) Techniques in Molecular Biology and Pharmacology Theory and Laboratory

Theoretical and practical knowledge of the foundational techniques used in pharmaceutical research in both academic research and the pharmaceutical and biotechnology industries. This course is not eligible for Credit/D/Fail grading.

Prerequisite: All of CHEM 211, CHEM 233, CHEM 235, PHAR 203, PHAR 204.

PHAR 305 (3) Clinical Epidemiology & Pharmaceutical Outcomes II

Population-level study designs and their critical appraisal skills in evidence evaluation, with a special emphasis on evidence-based pharmacy practice and the practical application of population-level data analysis and interpretation. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 205.

PHAR 306 (3) Medicinal Chemistry of High-Impact Pharmaceuticals in Major Diseases

Structure and mechanism of action of drugs used in the treatment of major chronic diseases: heart disease, cancer, lung disease, and diabetes. This course is not eligible for Credit/D/Fail grading.

Prerequisite: All of CHEM 233, PHAR 202.

PHAR 307 (4) Analytical Sciences Theory and Laboratory

Theoretical and practical knowledge of the analytical sciences commonly used in academic research as well as the pharmaceutical and biotechnology industries. This course is not eligible for Credit/D/Fail grading.

Prerequisite: All of CHEM 211, CHEM 233, CHEM 235, PHAR 204.

PHAR 308 (3) Systematic Pharmacology

General principles of pharmacodynamics and pharmacokinetics: drug action on nervous, cardiovascular, GI and endocrine systems; beneficial and detrimental effects of drug action. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 202.

PHAR 370 (3) Pharmaceutical Cases I

Application and problem solving in the pharmaceutical sciences. Integration of knowledge and skills from multiple courses to problem solve authentic cases and problems of increasing complexity. Development of self-directed learning skills. This course is not eligible for Credit/D/Fail grading.

PHAR 380 (1) Pharmaceutical Topics and Communication Seminar III

Preliminary skills and concepts for planning, delivering and critiquing a scientific presentation using selected topics in the pharmaceutical sciences. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 280.

PHAR 415 (4) Topics in Pharmaceutics and Biopharmaceutics

A study of selected topics in the field of pharmaceutics and biopharmaceutics. Registration restricted. Permission of instructor required. This course is not eligible for Credit/D/Fail grading. [2-0-0]

PHAR 421 (4) Precision Medicine

Skills and concepts in pharmacogenomics as applied to medical practice and dosing. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 203.

PHAR 422 (3) Pharmacoeconomics

Evidence evaluation skills and understanding the role of, and the methods and principles used in, health economics and economic evaluation in healthcare, with a focus on health technology assessment studies. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 305.

PHAR 423 (3) Pharmaceutical Outcomes Research

Principles of qualitative research design. Practical skills in ethics, recruitment, data collection and analysis. Application of epidemiologic and statistical knowledge to a research product in the area of health services outcomes. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 305.

PHAR 424 (3) Financing and Therapeutics in the Canadian Health Care System

Foundation in Canadian health care delivery systems and policies, with a focus on pharmaceutical policy and on comparison with other types of health care systems. This course is not eligible for Credit/D/Fail grading.

PHAR 425 (3) Biologics

Biologics as a therapeutic; how biologics are developed as drugs; synthesis and unique properties of biologics as drugs. This course is not eligible for Credit/D/Fail grading.

PHAR 426 (3) Advanced Anesthetics and Analgesics

Advanced concepts in anesthetic and analgesic drugs, their uses and abuses. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 308.

PHAR 427 (4) Drug Structures in Medicinal Chemistry

Therapeutically important privileged scaffolds and functional groups, and selectivity achieved through different chemical modifications. This course is not eligible for Credit/D/Fail grading.

Prerequisite: All of CHEM 233, PHAR 202.

PHAR 428 (3) Clinical Chemistry

Principles, practices and procedures of medical laboratory clinical chemistry. This course is not eligible for Credit/D/Fail grading.

Prerequisite: CHEM 211.

PHAR 429 (3) Adverse Drug Reactions

Molecular and physiological basis of common adverse drug reactions (ADRs). ADRs in the context of current understanding of drug metabolism and pharmacogenetics. New approaches to prediction, detection and treatment. This course is not eligible for Credit/D/Fail grading.

PHAR 430 (4) Biomolecular Pharmaceutical Chemistry

Chemical principles and their application to drugs used to regulate enzyme activity. This course is not eligible for Credit/D/Fail grading. [4-0-0]

PHAR 431 (3) Functional Foods

Functional food concepts related to efficacy and safety; examples of bioactive component-disease relationships; natural health products; approval of functional food and health claims; the importance of clinical studies in support of efficacy for health claims; market determinants of functional foods. Credit will be granted for only one of PHAR 431 or FNH 402. This course is not eligible for Credit/D/Fail grading.

Prerequisite: Fourth-year standing or permission of the instructor.

Equivalency: FNH 402.

PHAR 432 (3) Toxicology

Biochemical, cellular, and molecular processes that govern toxicity elicited by drugs and environmental toxins at the molecular, cellular, tissue, and organ system levels. Adverse drug reactions and precision medicine approaches to mitigate drug toxicity.

Prerequisite: PHAR 308.

PHAR 433 (3) Advanced Pharmacokinetics

Polyexponential pharmacokinetics, pharmacokinetic/pharmacodynamic modeling, pharmacokinetic predictions, physiologically-based pharmacokinetic modeling and population-based pharmacokinetic modeling. Credit will be granted for only one of PHAR 433 or PHAR 502. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 302.

PHAR 450 (2-9) d Selected Topics

This course is not eligible for Credit/D/Fail grading.

PHAR 470 (3) Pharmaceutical Cases II

Advanced application and problem solving in the pharmaceutical sciences. Integration of knowledge and skills from multiple courses to problem solve authentic cases and problems of increasing complexity. Further development and practice of self-directed learning skills. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 370.

PHAR 480 (3) Pharmaceutical Topics and Communication Seminar IV

Senior level skills and concepts for planning, delivering and critiquing a scientific seminar using extended topics in the pharmaceutical sciences and beyond. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 380.

PHAR 485 (15) Research Project

Provides research experience equivalent to one full-time term of work on a defined research project in an area of pharmaceutical research. This course is not eligible for Credit/D/Fail grading.

PHAR 491 (12) Honours Thesis

Research project and production of a thesis document in an area of pharmaceutical research according to national/international standards. This course is not eligible for Credit/D/Fail grading.

PHAR 495 (15) Practicum

Provides practicum experience equivalent to one full-time term of work in a professional area of pharmaceutical research This course is not eligible for Credit/D/Fail grading.

PHAR 497 (3-6) d Directed Studies in Pharmaceutical Sciences

Individual assignments involving library and laboratory investigation in an area of pharmaceutical research. This course is not eligible for Credit/D/Fail grading.

Prerequisite: PHAR 204.

PHAR 501 (12) Advanced Pharmacotherapeutics

Pharmacotherapeutic intervention in selected acute and chronic diseases and disorders. Emphasis is on recommendations for and monitoring of drug therapy. This course is not eligible for Credit/D/Fail grading. [3-6]

PHAR 502 (4) Advanced Concepts in Pharmacokinetics

Models of linear and dose-dependent systems in pharmacokinetics including sustained release, volumes of distribution, drug clearance, metabolite kinetics, multiple dosing and computer modelling. Credit will be granted for only one of PHAR 502 or PHAR 433. This course is not eligible for Credit/D/Fail grading. [4-0]

PHAR 506 (6) Critical Appraisal of Pharmacotherapy Literature

Identification, evaluation, and application of evidence relevant to improving clinical pharmacy practice and patient care. This course is not eligible for Credit/D/Fail grading. [3-0-0]

PHAR 508 (4) Advanced Applications in Clinical Pharmacokinetics

Pharmacokinetic applications in therapeutic drug monitoring and patient care; specific drugs and disease states; effects of age and concomitant drug administration. This course is not eligible for Credit/D/Fail grading. [4-0]

Prerequisite: PHAR 502.

PHAR 510 (2-6) d Advanced Pharmaceutics I

A study of physical and chemical properties of pharmaceutical systems with emphasis on formulation and preparative aspects. This course is not eligible for Credit/D/Fail grading.

PHAR 511 (2-6) d Advanced Pharmaceutics II

A study of problems in pharmaceutics with emphasis on biopharmaceutical aspects. This course is not eligible for Credit/D/Fail grading.

PHAR 515 (3) Nanomedicines

Nano-sized drug delivery systems and their interactions with biological systems. This course is not eligible for Credit/D/Fail grading.

PHAR 516 (2) Polymeric Drug and Protein Delivery

Advances in polymer-based drug delivery systems. This course is not eligible for Credit/D/Fail grading. [2-0]

PHAR 517 (2) Lipid-Based Drug Delivery

Advances in lipophilic drug delivery systems. This course is not eligible for Credit/D/Fail grading. [2-0]

PHAR 518 (4) Diagnostic Imaging and Radiopharmaceuticals

Radiation-related, optical, and other imaging methods (SPECT, PET, CT, MRI, microscopy, ultrasound) and their application in research. This course is not eligible for Credit/D/Fail grading. [3-4*-0]

PHAR 521 (1.5) Basic Theory & Practice of Scanning Electron Microscopy and Dynamic Light Scattering

Sample preparation; standard & advanced imaging techniques; image interpretation & quantification, applications in pharmaceutical research. This course is not eligible for Credit/D/Fail grading.

PHAR 522 (1) Basic Theory and Practice of Liquid Chromatography - Mass Spectrometry in Pharmaceutical Research

Fundamental and practical knowledge and skills to run liquid chromatography tandem mass spectrometry. This course is not eligible for Credit/D/Fail grading.

PHAR 523 (1) Basic Theory & Practice of Isothermal Titration Calorimetry

Isothermal titration calorimetry thermodynamic concepts and practical applications in measuring molecular interactions. This course is not eligible for Credit/D/Fail grading.

PHAR 524 (1) Cell Culture and New Biomedical Approaches

Basic cell culture techniques and novel insights into alternative methods in biomedical research. This course is not eligible for Credit/D/Fail grading.

PHAR 525 (4) Pharmaceutical Research Techniques I

Spectroscopic, GC, HPLC, LCMS and NMR analytical techniques for drug analysis, pharmacokinetics and metabolism. This course is not eligible for Credit/D/Fail grading. [2-6]

PHAR 526 (4) Pharmaceutical Research Techniques II

Immunological assays, capillary and gel electrophoresis, radioisotope techniques, PET, peptide analysis and receptor binding studies. This course is not eligible for Credit/D/Fail grading. [2-6-0]

PHAR 533 (12-24) d Clinical Clerkships I

Required clinical rotations of four weeks' duration in selected specialty areas in medicine and clinical pharmacy. This course is not eligible for Credit/D/Fail grading.

PHAR 534 (2-12) d Clinical Clerkships II

Elective clinical rotations of 4 weeks' duration in hospital, office or clinic locations. This course is not eligible for Credit/D/Fail grading.

PHAR 535 (1/2) d Pharm.D. Seminar

This course is not eligible for Credit/D/Fail grading.

PHAR 540 (2-6) d Topics in Pharmacology

Lectures and supervised studies in selected areas of pharmacology. Enrolment restricted. This course is not eligible for Credit/D/Fail grading.

PHAR 541 (3) Drug Metabolism and Toxicology

The biotransformation of drugs, pesticides, carcinogens and other foreign chemicals in animals and humans. The biochemical mechanisms responsible, particularly the cytochrome P-450 mono-oxygenases, will be emphasized. The formation of toxic reactive metabolites and their effects will be discussed. Enrolment restricted. This course is not eligible for Credit/D/Fail grading.

PHAR 542 (3) Central Nervous System Pharmacology

A course comprised of lectures, assigned readings and reports on selected topics dealing with drug actions in the central nervous system. Given in alternate years. Permission of instructor required. This course is not eligible for Credit/D/Fail grading.

PHAR 543 (3) Advanced Laboratory in Pharmacology

A laboratory course giving instruction in the methods and techniques used in pharmacological research. Registration limited. This course is not eligible for Credit/D/Fail grading. [0-6]

PHAR 545 (3) Cardiovascular Pharmacology

A course composed of lectures, assigned readings and conferences dealing with aspects of drug actions and cardiovascular function. Topics include the role of adenylate cyclase in cardiac function, the role of calcium in myocardial contractility and the effect of drugs on myocardial and vascular function. Enrolment restricted. Given in alternate years. This course is not eligible for Credit/D/Fail grading.

PHAR 546 (3) Etiology of Diabesity, from Cell to Society

Advanced course on pathophysiology and patient care for obesity and diabetes focusing on healthcare quality improvement, patient safety and optimising outcomes. This course is not eligible for Credit/D/Fail grading.

Equivalency: PHRM 346.

PHAR 548 (2) M.Sc. Seminar

Attendance at regular seminars throughout the session and presentation of one or more papers on selected topics. This course is not eligible for Credit/D/Fail grading.

PHAR 549 (6/12) c Master's Thesis

This course is not eligible for Credit/D/Fail grading.

PHAR 550 (1-6) c Directed Studies

This course is not eligible for Credit/D/Fail grading.

PHAR 554 (3) Advanced Hospital Pharmacy Management

Institutional, professional and regulatory factors that influence the planning, implementation and control of pharmacy services in hospitals. Permission of instructor required. This course is not eligible for Credit/D/Fail grading. [3-0]

PHAR 560 (3) Advanced Economic Evaluation in Health Care

Economic evaluation of health technologies, considering, in detail, the policy context for the use of economic evaluation. This course is not eligible for Credit/D/Fail grading.

Prerequisite: SPPH 541. Or equivalent training.

Equivalency: SPPH 549.

PHAR 561 (3) Pharmacoepidemiology

Principles and applications of pharmacoepidemiology. Practical skills in designing, conducting, and appraising studies of medications in large populations. This course is not eligible for Credit/D/Fail grading.

Prerequisite: Previous coursework in statistics or biostatistics.

PHAR 570 (2) Physical Assessment

Principles of and clinical experience in physical assessment of patients for monitoring of drug efficacy and toxicity; interpretation of objective patient data by the clinical pharmacist. This course is not eligible for Credit/D/Fail grading. [2-0]

PHAR 590 (3) Research in the Pharmaceutical Sciences: Principles and Methods

This course is not eligible for Credit/D/Fail grading.

PHAR 591 (1) Scholarly Integrity and Research Ethics

This course is not eligible for Credit/D/Fail grading.

PHAR 592 (1-3) c Fundamentals of the Pharmaceutical Sciences Disciplines

This course is not eligible for Credit/D/Fail grading.

PHAR 648 (2) Seminar for Ph.D. Students

Attendance at regular seminars throughout the session and presentation of one or more papers on selected topics. This course is not eligible for Credit/D/Fail grading.

PHAR 649 (0) Doctoral Dissertation

This course is not eligible for Credit/D/Fail grading.