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Medical Genetics, Faculty of Medicine

MEDG: Medical Genetics

MEDG 410 (3) Immunogenetics
Molecular basis of lymphocyte development, activation and adhesion; immunogenetics and the major histocompatibility complex. Consult the Credit Exclusion list within the Faculty of Science section of the Calendar. [3-0-1]
Prerequisite: MICB 302 and one of BIOL 334, BIOL 335. A standing of "B" or better is recommended.
Equivalency: MICB 402.
MEDG 419 (3) Developmental Origin of Human Disorders
Genetic and epigenetic determinants of development from conception to birth. Topics include development of the neural tube, face, heart, endoderm, blastocyst, embryonic stem cells, gastrulation, genomic imprinting, placental complications, chromosomal abnormalities and prenatal diagnosis. Discussions based on published research articles. [3-0-1]
Prerequisite: One of BIOL 234, BIOL 334 and one of BIOL 331, BIOL 335. A standing of 'B' or higher recommended.
MEDG 420 (3) Human Genomics and Medical Genetics
Sequence and structure of the human genome. Human genetic evolution. Identification of genes affecting normal and pathological variation. Molecular mechanisms of genetic diseases and disorders. Medical applications of human genetics. [3-0-0]
Prerequisite: BIOL 335. A standing of 'B' or higher is recommended.
MEDG 421 (3) Genetics and Cell Biology of Cancer
Molecular mechanisms of oncogenes and tumor suppressors and the effects of oncogenic mutations on the biology of cancer cells. [3-0-0]
Prerequisite: BIOL 335 and one of BIOC 300, BIOC 302, BIOC 303, BIOL 350.
MEDG 448 (3/6) d Directed Studies
A supervised individual program of study of a topic to be agreed upon by a member of faculty and the student. Permission of the appropriate supervisor and the department head is required.
MEDG 505 (3) Genome Analysis
Investigation of genetic information as it is organized within genomes, genetic and physical map construction, sequencing technologies, gene identification, database accessing and integration, functional organization of genomes from contemporary, historic and evolutionary perspectives. This course is not eligible for Credit/D/Fail grading.
Prerequisite: All of BIOL 334, BIOL 300.
MEDG 510 (3) Advanced Immunogenetics
Cell-cell interaction, intracellular control mechanisms, analysis of complex physiological systems using transgenic animals and molecular approaches. This course is not eligible for Credit/D/Fail grading. [3-0]
Equivalency: MICB 502.
MEDG 515 (3) Mammalian Developmental Genetics
Genetic determination of morphology and differentiation in human and other mammalian embryos. This course is not eligible for Credit/D/Fail grading. [3-0]
Prerequisite: BIOL 335.
MEDG 520 (3) Advanced Human Molecular Genetics
Genetic variation, genome analysis, cloning of genes for diseases and normal functions, mutation detection, animal models of human genetic disease. This course is not eligible for Credit/D/Fail grading. [3-0]
Prerequisite: BIOL 334.
MEDG 521 (3) Molecular and Cell Biology of Cancer
Focuses on molecular and cell biology of cancer through a series of lectures, reviews, student presentations and discussion. This course is not eligible for Credit/D/Fail grading. [3-0]
Prerequisite: BIOL 334.
Equivalency: PATH 531.
MEDG 525 (3) Medical Population Genetics
Population genetics, genetic epidemiology and methodology in data analysis applicable to the study of human genes, traits or diseases. This course is not eligible for Credit/D/Fail grading. [3-0]
Prerequisite: BIOL 335.
MEDG 530 (3) Human Genetics
Human Mendelian and non-Mendelian inheritance and clinical applications of genetics. This course is not eligible for Credit/D/Fail grading. [3-0]
Prerequisite: BIOL 335.
MEDG 535 (3) Genetics and Ethics
This course is intended to serve the diverse needs of genetic counseling students, research graduate students in genetics, genetic residents and clinical fellows, other health professional students, and graduate students from other sciences and humanities. This course is not eligible for Credit/D/Fail grading. [3-0]
MEDG 540 (3) Seminar
All seminars will be presented by graduate students in the Department of Medical Genetics. Although students will be encouraged to attend these seminars throughout their graduate studies, credit will only be available for one year. This course is not eligible for Credit/D/Fail grading. [2-0]
MEDG 545 (3) Current Topics in Medical Genetics Research
Critical discussion of current primary research literature in medical genetics. This course is not eligible for Credit/D/Fail grading.
MEDG 548 (3-6) c Directed Studies
A series of laboratory sessions, directed readings and directed counselling interviews related to selected areas of Medical Genetics. This advanced course may be taken upon approval of the department head. This course is not eligible for Credit/D/Fail grading.
MEDG 549 (12) M.Sc. Thesis
This course is not eligible for Credit/D/Fail grading.
MEDG 550 (6) Concepts in Clinical Genetics for Genetic Counselling
Practical applications, theories, and principles of medical genetics as they apply to genetic counselling. This course is not eligible for Credit/D/Fail grading. [4-0-0]
Prerequisite: Acceptance into M.Sc. Genetic Counselling program.
MEDG 560 (2) Genetic Counselling Seminar
Medical and genetic interviewing and family history taking; decision making; family dynamics; impact of congenital defects, genetic disease, and chronic disease on individuals and families; support groups and other community resources; computer resources; cross-cultural issues. This course is not eligible for Credit/D/Fail grading. [2-0-0]
Prerequisite: Acceptance into M.Sc. Genetic Counselling program.
MEDG 565 (2) Advanced Genetic Counselling Seminar
Patient attitudes toward genetic counselling; the grieving process in response to pregnancy loss, death, and disability; risk perception, attitudes toward prenatal testing, dealing with results of genetic testing, crisis counselling, giving bad news; ethical dilemmas; legal and professional issues. This course is not eligible for Credit/D/Fail grading. [0-2]
Prerequisite: MEDG 560. And acceptance into M.Sc. Genetic Counselling program.
MEDG 570 (3) Introductory Clinical and Laboratory Rotation
Clinical experience in prenatal procedures and counselling; teratogen counselling. Clinically relevant experience in cytogenetics, molecular, biochemical disease and embryopathology laboratories. This course is not eligible for Credit/D/Fail grading. [0-5]
Prerequisite: Acceptance into M.Sc. Genetic Counselling program.
MEDG 575 (10) Advanced Clinical Rotation
In-depth clinical experience in general and prenatal genetic counselling. This course is not eligible for Credit/D/Fail grading. [0-15]
Prerequisite: MEDG 570. And acceptance into M.Sc. Genetic Counselling program.
MEDG 649 (0) Doctoral Dissertation
MEDG 702 (0) Clinical Genetics Clinic
A rotation for three months through the Clinical Genetics Clinic dealing with the techniques of diagnosis and counselling, and of the prenatal diagnoses of genetic disease and genetic counselling relative to congenital malformations and failures of reproduction.

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