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Pharmacology and Therapeutics, Faculty of Medicine

PCTH: Pharmacology and Therapeutics

PCTH 201 (3) Drugs and Society
Introductory principles of drug action. Historical and present day medical and non-medical use of drugs. [3-0]
Prerequisite: One of Biology 12, BIOL 111, BIOL 112, BIOL 153, BIOL 155, or SCIE 001. Second-year standing is required.
PCTH 300 (6) Introduction to Pharmacology
The concepts, language and techniques of scientific pharmacology. Intended primarily for Honours and Major students in Pharmacology. [3-3-0]
Prerequisite: Either (a) all of BIOL 200, BIOL 201, CHEM 233, CHEM 235 or (b) all of BIOL 200, BIOL 201, CHEM 203, CHEM 204; and CHEM 211 and one of CHEM 205, CHEM 201. Permission of the undergraduate adviser is required.
PCTH 302 (3) Introductory Pharmacology Laboratory
A series of experimental demonstrations and individual laboratory experiments illustrating the basic principles of pharmacology. [1-3*]
Corequisite: PCTH 300.
PCTH 305 (6) Basic Human Pharmacology
Lectures and assigned reading on the effects, mechanisms of action, absorption, distribution, fate and excretion of major classes of therapeutic agents. Indications for the use of particular drugs will be discussed in terms of risk versus benefit for the individual and for society. [3-0-0; 3-0-0]
Prerequisite: One of BIOL 201, BIOC 202, BIOC 203.
Corequisite: CAPS 301.
PCTH 325 (3) Rational Basis of Drug Therapy
The principles and applications underlying the action and disposition of therapeutic agents (including alternative medicines) in the body. Use of drugs as tools in experimental research. [3-0]
Prerequisite: One of BIOL 201, BIOC 202, BIOC 203, BIOC 300.
PCTH 398 (3) Co-operative Work Placement I
Approved and supervised technical work experience in an industrial research setting for a minimum of 3.5 months. Technical report required. Restricted to students admitted to the Co-operative Education Program in Pharmacology. This course is not eligible for Credit/D/Fail grading.
Prerequisite: PCTH 300.
PCTH 399 (3) Co-operative Work Placement II
Approved and supervised technical work experience in an industrial research setting for a minimum of 3.5 months. Technical report required. Restricted to students admitted to the Co-operative Education Program in Pharmacology. This course is not eligible for Credit/D/Fail grading.
Prerequisite: PCTH 398.
PCTH 400 (6) Systematic Pharmacology
Lectures and discussions in scientific pharmacology. All aspects of the study of drugs will be covered, but the course will concentrate on the scientific aspects of the pharmacology of neurohumoral transmission, mathematics of pharmacology, cardiovascular and clinical pharmacology, and to a lesser extent on the pharmacology of various organs and tissues. [3-0-1*]
Prerequisite: PCTH 300.
PCTH 402 (6) Systematic Pharmacology Laboratory
A series of demonstrated, group, and individual laboratory experiments designed to illustrate the concepts and hypotheses of pharmacology. The course is restricted to Honours students in Pharmacology, but may be taken by others with permission of the department head. [0-9; 0-9]
Prerequisite: PCTH 300.
PCTH 404 (3) Drug Assay and Pharmacometrics
The techniques, including methods of statistical analysis, used to detect and measure the actions of endogenous or exogenous chemicals, using chemical assays and bioassays as appropriate. Enrolment limited to students in Pharmacology and others with permission of the department head. [1-0; 2-0]
Prerequisite: All of PCTH 300, BIOL 300.
PCTH 425 (8) Medical Pharmacology
A lecture and laboratory course covering the fundamental pharmacological action of drugs. Both terms. This course is not eligible for Credit/D/Fail grading.
PCTH 448 (2-6) c Directed Studies in Pharmacology
Advanced investigation of a specific topic in Pharmacology.
PCTH 449 (3/6) d Honours Thesis
A research problem directed by a faculty member. Restricted to Honours Pharmacology students.
PCTH 451 (3) Review of Clinical Pharmacology
This course has been designed as a basic science elective for third-year medical students.
Prerequisite: Departmental approval required.
PCTH 453 (2) Advanced Therapeutics
A lecture, assigned problems, and discussion course dealing with practical aspects of therapeutics. This course is designed to give fourth-year medical students some practical experience in the science of drug prescribing.
PCTH 498 (3) Co-operative Work Placement III
Approved and supervised technical work experience in an industrial research setting for a minimum of 3.5 months. Technical report required. Restricted to students admitted to the Co-operative Education Program in Pharmacology. This course is not eligible for Credit/D/Fail grading.
Prerequisite: PCTH 399.
PCTH 499 (3) Co-operative Work Placement IV
Approved and supervised technical work experience in an industrial research setting for a minimum of 3.5 months. Normally taken during the summer after fourth year. Technical report required. Restricted to students admitted to the Co-operative Education Program in Pharmacology. This course is not eligible for Credit/D/Fail grading.
Prerequisite: PCTH 498.
PCTH 500 (3) Molecular Aspects of Drug Action at the Membrane Level
Lectures, discussions and assigned reading on actions of drugs on ion channels, receptors and intracellular processes and the methodologies used including electrophysiology, fluorescence measurements, molecular neurobiology and microdialysis. Given in even-numbered and alternate years. This course is not eligible for Credit/D/Fail grading.
PCTH 501 (3) Structure-Activity Relationships in Pharmacology
Lectures, discussions and assigned reading on physicochemical approaches to drug design - the relationship between molecular structure and pharmacological activity in various representative classes of drugs. Given in odd-numbered and alternate years. This course is not eligible for Credit/D/Fail grading.
PCTH 502 (4) Drugs and Intercellular Communication (including Neuropharmacology)
Lectures, discussions and assigned reading on the actions of drugs on the production, release and cellular effects of hormones and neurotransmitters. Given in odd-numbered and alternate years. This course is not eligible for Credit/D/Fail grading.
PCTH 512 (3) Experimental Design and Analysis in Pharmacology
A series of lectures, tutorials and exercises designed to improve student skills in the design and statistical analyses of pharmacological experiments. This course is not eligible for Credit/D/Fail grading.
PCTH 513 (4) Pharmacology of Anaesthesia
Pharmacology of drugs used in anaesthesia. Conferences, assigned reading and laboratory exercises demonstrating the actions of drugs as currently applied in the practice of anaesthesia. This course is not eligible for Credit/D/Fail grading.
Prerequisite: Permission of the department head is required.
PCTH 514 (1) Seminar in Pharmacology or Therapeutics
To give students experience in the presentation of data and to enhance communication skills in the discussion of scientific topics. All students will present at least one seminar during their graduate work and would be expected to attend all seminars. This course is not eligible for Credit/D/Fail grading.
PCTH 548 (2-6) c Directed Studies in Pharmacology
In special cases, with the approval of the department head, advanced courses may be arranged. This course is not eligible for Credit/D/Fail grading.
PCTH 549 (12) M.Sc. Thesis
This course is not eligible for Credit/D/Fail grading.
PCTH 649 (0) Doctoral Dissertation

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